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Tag: break from treatment leads to healthier bones


Posted on February 22, 2021 in News

American researchers have found that bone density despite interruption of therapy remains stable during three years. Bisphosphonates are a popular class of drugs for osteoporosis, which benefits is documented in numerous studies. Unfortunately they lead in a certain percentage of cases to fractures of the thigh bone, which can lead to protracted and complicated healing phases entail. “Bisphosphonates are potentially harmful substances if consumed over a long period. Yet you knew not so far how long osteoporosis patients without treatment can stay and prevent this damaging situation,”said Dr. Pauline Camacho, Director of studies and Director of the Loyola University osteoporosis and metabolic bone disease center. “Our study shows for the first time, that the bone despite interruption of therapy several years remain stable.” So far was that a therapy with bisphosphonates should be interrupted after about four to five years for a period of time.

However, the length of the suspension was unknown, what the researchers of the Loyola University took on the occasion due to precise provisions of the bone density and bone loss to be able to give a general recommendation. 139 patients with osteoporosis or osteopenia, a precursor of osteoporosis have been integrated into the study. On average, the patients had a duration of therapy with bisphosphonates 6.8 years before she began the therapy interruption in the course of the study. Five conch fractions were diagnosed during the drug-free, without a significant loss of bone density would have to be detected. However the bone resorption resumed after six months. The type of Bisphosphonate had just as little effect on bone density, such as the previous duration of therapy. “This study is certainly not exhaustive and must be validated by other studies. But we have seen that an interruption of therapy can be carried out without hindrance of at least three years,”said Dr.

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